12.11.2024
Dr Habil. Krzysztof Chlebus, from the 1st Department of Cardiology of the Medical University of Gdańsk, coordinator of the National Center for Familial Hypercholesterolemia in Gdańsk, is co-author of the publication “Association of BMI, lipid-lowering medication, and age with prevalence of type 2 diabetes in adults with heterozygous familial hypercholesterolaemia: a worldwide cross-sectional study” in the prestigious journal The Lancet Diabetes Endocrinology.
The journal has an Impact Factor of 44 and is ranked number one worldwide among journals in endocrinology and metabolism (2023 Journal Citation Reports®, Clarivate 2024), and has a CiteScore of 61.5. What’s more, it also ranks first among scientific journals in endocrinology, diabetes, metabolism, and internal medicine and endocrinology journals (Scopus).
The study analyzed the prevalence of type 2 diabetes in a cohort of 24,784 patients with heterozygous familial hypercholesterolemia from 44 countries in the global FHSC registry. No protective effect of the FH genetic mutation on the incidence of type 2 diabetes was confirmed, as previously reported in national registry analyzes from the Netherlands, Spain and Canada. In addition, the strongest risk factors for diabetes in the highest cardiovascular risk patients with the genetic mutation were identified, and differences in diabetes prevalence between populations in all WHO regions were described.
The article is the result of the collaboration that has been ongoing since 2015 of the EAS FHSC ( European Arterosclerosis Society, Familial Hypercholesterolaemia Studies Collaboration ), an initiative that brings together researchers from around the world involved in the care of people affected by familial hypercholesterolemia.The National Center for Familial Hypercholesterolemia, created and led by Dr. Habil. Krzysztof Chlebus and his team, has been involved in the work of the FHSC since its establishment.
Read more at: https://www.thelancet.com/journals/landia/article/PIIS2213-8587(24)00221-3/fulltext.